Mast cell activation syndrome: An immune system stuck in self-defence – RACGP

Assaults on our immune system in our current era come from many directions; industrial chemical toxicant burdens, biotoxin accumulation from harmful moulds, chronic and recurrent infective burdens, dysbiotic microbiomes, endothelial dysfunction, psychological stress, and these to name only a few.

The many and growing environmental threats amount to, in up to 17% of the population cited in recent studies, an auto-inflammatory illness known as Mast Cell Activation Syndrome (MCAS), characterised by excessive cytokine signalling in response to perceived biological threats.

Understanding how to recognise, diagnose, and treat MCAS underpins an area of medicine essential to meaningfully intervening in our immune-sensitive, multi-system inflamed patient cohort.

Learning outcomes

  • Identify MCAS in general practice patients in Australia (including clinical presentation, symptoms, signs, and diagnosis).
  • Outline an integrative approach to MCAS management.
  • Explore underlying aetiology of MCAS

Facilitators

Dr Tamara Nation – MBBS PhD FRACGP FACNEM

Dr Inanch Mehmet – Deputy Chair, RACGP Specific Interests Integrative Medicine

Dr Eric Miller – Deputy Chair, RACGP Specific Interests Integrative medicine

Speaker

Dr Nicholas Morgan – B.Med, F.RACGP, F.ACNEM, Dip.TM&H

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